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Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology–Genomic Integration Analysis

BACKGROUND: The intra-tumor diversity of cancer cells is under intense investigation; however, little is known about the heterogeneity of the tumor microenvironment that is key to cancer progression and evolution. We aimed to assess the degree of microenvironmental heterogeneity in breast cancer and...

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Detalles Bibliográficos
Autores principales: Natrajan, Rachael, Sailem, Heba, Mardakheh, Faraz K., Arias Garcia, Mar, Tape, Christopher J., Dowsett, Mitch, Bakal, Chris, Yuan, Yinyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755617/
https://www.ncbi.nlm.nih.gov/pubmed/26881778
http://dx.doi.org/10.1371/journal.pmed.1001961