Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites

While the dynamin GTPase Drp1 plays a critical role during mitochondrial fission, mechanisms controlling its recruitment to fission sites are unclear. A current assumption is that cytosolic Drp1 is recruited directly to fission sites immediately prior to fission. Using live-cell microscopy, we find...

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Detalles Bibliográficos
Autores principales: Ji, Wei-ke, Hatch, Anna L, Merrill, Ronald A, Strack, Stefan, Higgs, Henry N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755738/
https://www.ncbi.nlm.nih.gov/pubmed/26609810
http://dx.doi.org/10.7554/eLife.11553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755738/
https://www.ncbi.nlm.nih.gov/pubmed/26609810
http://dx.doi.org/10.7554/eLife.11553

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