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Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites
While the dynamin GTPase Drp1 plays a critical role during mitochondrial fission, mechanisms controlling its recruitment to fission sites are unclear. A current assumption is that cytosolic Drp1 is recruited directly to fission sites immediately prior to fission. Using live-cell microscopy, we find...
Autores principales: | Ji, Wei-ke, Hatch, Anna L, Merrill, Ronald A, Strack, Stefan, Higgs, Henry N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755738/ https://www.ncbi.nlm.nih.gov/pubmed/26609810 http://dx.doi.org/10.7554/eLife.11553 |
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