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A mathematical model explains saturating axon guidance responses to molecular gradients

Correct wiring is crucial for the proper functioning of the nervous system. Molecular gradients provide critical signals to guide growth cones, which are the motile tips of developing axons, to their targets. However, in vitro, growth cones trace highly stochastic trajectories, and exactly how molec...

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Detalles Bibliográficos
Autores principales: Nguyen, Huyen, Dayan, Peter, Pujic, Zac, Cooper-White, Justin, Goodhill, Geoffrey J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755759/
https://www.ncbi.nlm.nih.gov/pubmed/26830461
http://dx.doi.org/10.7554/eLife.12248