Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

Regulatory T (T(reg)) cells respond to immune and inflammatory signals to mediate immunosuppression, but how functional integrity of T(reg) cells is maintained under activating environments remains elusive. Here we found that autophagy was active in T(reg) cells and supported their lineage stability...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Jun, Long, Lingyun, Yang, Kai, Guy, Cliff, Shrestha, Sharad, Chen, Zuojia, Wu, Chuan, Vogel, Peter, Neale, Geoffrey, Green, Douglas R, Chi, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755832/
https://www.ncbi.nlm.nih.gov/pubmed/26808230
http://dx.doi.org/10.1038/ni.3365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755832/
https://www.ncbi.nlm.nih.gov/pubmed/26808230
http://dx.doi.org/10.1038/ni.3365

Ejemplares similares