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Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis
Regulatory T (T(reg)) cells respond to immune and inflammatory signals to mediate immunosuppression, but how functional integrity of T(reg) cells is maintained under activating environments remains elusive. Here we found that autophagy was active in T(reg) cells and supported their lineage stability...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755832/ https://www.ncbi.nlm.nih.gov/pubmed/26808230 http://dx.doi.org/10.1038/ni.3365 |