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Protonation of a Glutamate Residue Modulates the Dynamics of the Drug Transporter EmrE
Secondary active transport proteins play a central role in conferring bacterial multidrug resistance. In this work, we investigated the proton-coupled transport mechanism for the Escherichia coli drug efflux pump EmrE using nuclear magnetic resonance (NMR) spectroscopy. Our results show that the glo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755857/ https://www.ncbi.nlm.nih.gov/pubmed/26751516 http://dx.doi.org/10.1038/nchembio.1999 |