Epigenetic regulation of Il12 and Il23 gene expression and autoimmune inflammation by the deubiquitinase Trabid

The proinflammatory cytokines interleukin 12 (IL-12) and IL-23 connect innate and adaptive immune responses and are also involved in autoimmune and inflammatory diseases. Here we describe an epigenetic mechanism of Il12 and Il23 gene regulation involving the deubiquitinase Trabid. Deletion of Zranb1...

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Detalles Bibliográficos
Autores principales: Jin, Jin, Xie, Xiaoping, Xiao, Yichuan, Hu, Hongbo, Zou, Qiang, Cheng, Xuhong, Sun, Shao-Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755875/
https://www.ncbi.nlm.nih.gov/pubmed/26808229
http://dx.doi.org/10.1038/ni.3347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755875/
https://www.ncbi.nlm.nih.gov/pubmed/26808229
http://dx.doi.org/10.1038/ni.3347

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