Optimized Blanching Reduces the Host Cell Protein Content and Substantially Enhances the Recovery and Stability of Two Plant-Derived Malaria Vaccine Candidates

Plants provide an advantageous expression platform for biopharmaceutical proteins because of their low pathogen burden and potential for inexpensive, large-scale production. However, the purification of target proteins can be challenging due to issues with extraction, the removal of host cell protei...

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Detalles Bibliográficos
Autores principales: Menzel, Stephan, Holland, Tanja, Boes, Alexander, Spiegel, Holger, Bolzenius, Johanna, Fischer, Rainer, Buyel, Johannes F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756251/
https://www.ncbi.nlm.nih.gov/pubmed/26925077
http://dx.doi.org/10.3389/fpls.2016.00159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756251/
https://www.ncbi.nlm.nih.gov/pubmed/26925077
http://dx.doi.org/10.3389/fpls.2016.00159

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