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Optimized Blanching Reduces the Host Cell Protein Content and Substantially Enhances the Recovery and Stability of Two Plant-Derived Malaria Vaccine Candidates
Plants provide an advantageous expression platform for biopharmaceutical proteins because of their low pathogen burden and potential for inexpensive, large-scale production. However, the purification of target proteins can be challenging due to issues with extraction, the removal of host cell protei...
Autores principales: | Menzel, Stephan, Holland, Tanja, Boes, Alexander, Spiegel, Holger, Bolzenius, Johanna, Fischer, Rainer, Buyel, Johannes F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756251/ https://www.ncbi.nlm.nih.gov/pubmed/26925077 http://dx.doi.org/10.3389/fpls.2016.00159 |
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