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Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine
The ability to predict the future behavior of an individual cancer is crucial for precision cancer medicine. The discovery of extensive intratumor heterogeneity and ongoing clonal adaptation in human tumors substantiated the notion of cancer as an evolutionary process. Random events are inherent in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756277/ https://www.ncbi.nlm.nih.gov/pubmed/26949746 http://dx.doi.org/10.1016/j.trecan.2015.11.003 |