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Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine

The ability to predict the future behavior of an individual cancer is crucial for precision cancer medicine. The discovery of extensive intratumor heterogeneity and ongoing clonal adaptation in human tumors substantiated the notion of cancer as an evolutionary process. Random events are inherent in...

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Detalles Bibliográficos
Autores principales: Lipinski, Kamil A., Barber, Louise J., Davies, Matthew N., Ashenden, Matthew, Sottoriva, Andrea, Gerlinger, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756277/
https://www.ncbi.nlm.nih.gov/pubmed/26949746
http://dx.doi.org/10.1016/j.trecan.2015.11.003