A collagen-binding EGFR antibody fragment targeting tumors with a collagen-rich extracellular matrix

Many tumors over-express collagen, which constitutes the physical scaffold of tumor microenvironment. Collagen has been considered to be a target for cancer therapy. The collagen-binding domain (CBD) is a short peptide, which could bind to collagen and achieve the sustained release of CBD-fused prot...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Hui, Li, Xiaoran, Wang, Bin, Chen, Bing, Zhao, Yannan, Sun, Jie, Zhuang, Yan, Shi, Jiajia, Shen, He, Zhang, Zhijun, Dai, Jianwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756367/
https://www.ncbi.nlm.nih.gov/pubmed/26883295
http://dx.doi.org/10.1038/srep18205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756367/
https://www.ncbi.nlm.nih.gov/pubmed/26883295
http://dx.doi.org/10.1038/srep18205

Ejemplares similares