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Wnt11 Gene Therapy with Adeno-associated Virus 9 Improves Recovery from Myocardial Infarction by Modulating the Inflammatory Response

Acute myocardial infarction induces activation of the acute phase response and infiltration of leukocytes to the infarcted area. Moreover, myocardium that is remote from ischemic area also becomes inflamed. Inflammatory reaction clears dead cells and matrix debris, while prolongation or expansion of...

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Detalles Bibliográficos
Autores principales: Morishita, Yoshihiro, Kobayashi, Koichi, Klyachko, Ekaterina, Jujo, Kentaro, Maeda, Kengo, Losordo, Douglas W., Murohara, Toyoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756373/
https://www.ncbi.nlm.nih.gov/pubmed/26882996
http://dx.doi.org/10.1038/srep21705