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Design and rationale of the ATHENA study – A 12-month, multicentre, prospective study evaluating the outcomes of a de novo everolimus-based regimen in combination with reduced cyclosporine or tacrolimus versus a standard regimen in kidney transplant patients: study protocol for a randomised controlled trial

BACKGROUND: Immunosuppression with calcineurin inhibitors remains the mainstay of treatment after kidney transplantation; however, long-term use of these drugs may be associated with nephrotoxicity. In this regard, the current approach is to optimise available immunosuppressive regimens to reduce th...

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Detalles Bibliográficos
Autores principales: Sommerer, Claudia, Suwelack, Barbara, Dragun, Duska, Schenker, Peter, Hauser, Ingeborg A., Nashan, Björn, Thaiss, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756406/
https://www.ncbi.nlm.nih.gov/pubmed/26888217
http://dx.doi.org/10.1186/s13063-016-1220-9