Reclassification of genetic-based risk predictions as GWAS data accumulate

BACKGROUND: Disease risk assessments based on common genetic variation have gained widespread attention and use in recent years. The clinical utility of genetic risk profiles depends on the number and effect size of identified loci, and how stable the predicted risks are as additional loci are disco...

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Detalles Bibliográficos
Autores principales: Krier, Joel, Barfield, Richard, Green, Robert C., Kraft, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756503/
https://www.ncbi.nlm.nih.gov/pubmed/26884246
http://dx.doi.org/10.1186/s13073-016-0272-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756503/
https://www.ncbi.nlm.nih.gov/pubmed/26884246
http://dx.doi.org/10.1186/s13073-016-0272-5

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