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Novel fusion proteins for the antigen-specific staining and elimination of B cell receptor-positive cell populations demonstrated by a tetanus toxoid fragment C (TTC) model antigen

BACKGROUND: In an earlier study we developed a unique strategy allowing us to specifically eliminate antigen-specific murine B cells via their distinct B cell receptors using a new class of fusion proteins. In the present work we elaborated our idea to demonstrate the feasibility of specifically add...

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Detalles Bibliográficos
Autores principales: Klose, Diana, Saunders, Ute, Barth, Stefan, Fischer, Rainer, Jacobi, Annett Marita, Nachreiner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756516/
https://www.ncbi.nlm.nih.gov/pubmed/26883813
http://dx.doi.org/10.1186/s12896-016-0249-x