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A web-oriented software for the optimization of pooled experiments in NGS for detection of rare mutations

BACKGROUND: The cost per patient of next generation sequencing for detection of rare mutations may be significantly reduced using pooled experiments. Recently, some techniques have been proposed for the planning of pooled experiments and for the optimal allocation of patients into pools. However, th...

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Detalles Bibliográficos
Autores principales: Evangelista, Daniela, Zuccaro, Antonio, Lančinskas, Algirdas, Žilinskas, Julius, Guarracino, Mario R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756526/
https://www.ncbi.nlm.nih.gov/pubmed/26888663
http://dx.doi.org/10.1186/s13104-016-1889-6