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A web-oriented software for the optimization of pooled experiments in NGS for detection of rare mutations
BACKGROUND: The cost per patient of next generation sequencing for detection of rare mutations may be significantly reduced using pooled experiments. Recently, some techniques have been proposed for the planning of pooled experiments and for the optimal allocation of patients into pools. However, th...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756526/ https://www.ncbi.nlm.nih.gov/pubmed/26888663 http://dx.doi.org/10.1186/s13104-016-1889-6 |