Physiological evidence for diversification of IFNα- and IFNβ-mediated response programs in different autoimmune diseases

BACKGROUND: Activation of the type I interferon (IFN) response program is described for several autoimmune diseases, including systemic lupus erythematosus (SLE), multiple sclerosis (MS), myositis (IIM) and rheumatoid arthritis (RA). While IFNα contributes to SLE pathology, IFNβ therapy is often ben...

Descripción completa

Detalles Bibliográficos
Autores principales: de Jong, Tamarah D., Vosslamber, Saskia, Mantel, Elise, de Ridder, Sander, Wesseling, John G., van der Pouw Kraan, Tineke C. T. M., Leurs, Cyra, Hegen, Harald, Deisenhammer, Florian, Killestein, Joep, Lundberg, Ingrid E., Vencovsky, Jiri, Nurmohamed, Mike T., van Schaardenburg, Dirkjan, Bultink, Irene E. M., Voskuyl, Alexandre E., Pegtel, D. Michiel, van der Laken, Conny J., Bijlsma, Johannes W. J., Verweij, Cornelis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756531/
https://www.ncbi.nlm.nih.gov/pubmed/26882897
http://dx.doi.org/10.1186/s13075-016-0946-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756531/
https://www.ncbi.nlm.nih.gov/pubmed/26882897
http://dx.doi.org/10.1186/s13075-016-0946-9

Ejemplares similares