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Universal minicircle sequence binding protein of Leishmania donovani regulates pathogenicity by controlling expression of cytochrome-b

BACKGROUND: Leishmania contains a concatenated mitochondrial DNA, kDNA. Universal minicircle sequence binding protein (UMSBP), a mitochondrial protein, initiates kDNA replication by binding with a conserved universal minicircle sequence (UMS) of kDNA. Here, we describe first time in L. donovani the...

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Detalles Bibliográficos
Autores principales: Singh, Ruby, Purkait, Bidyut, Abhishek, Kumar, Saini, Savita, Das, Sushmita, Verma, Sudha, Mandal, Abhishek, Ghosh, Ayan Kr., Ansari, Yousuf, Kumar, Ashish, Sardar, Abul H., Kumar, Ajay, Parrack, Pradeep, Das, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756535/
https://www.ncbi.nlm.nih.gov/pubmed/26889377
http://dx.doi.org/10.1186/s13578-016-0072-z