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HIV coreceptor tropism determination and mutational pattern identification

In the early stages of infection, Human Immunodeficiency Virus Type 1 (HIV-1) generally selects CCR5 as the primary coreceptor for entering the host cell. As infection progresses, the virus evolves and may exhibit a coreceptor-switch to CXCR4. Accurate determination coreceptor usage and identificati...

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Detalles Bibliográficos
Autores principales: Shen, Hui-Shuang, Yin, Jason, Leng, Fei, Teng, Rui-Fang, Xu, Chao, Xia, Xia-Yu, Pan, Xian-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756667/
https://www.ncbi.nlm.nih.gov/pubmed/26883082
http://dx.doi.org/10.1038/srep21280