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A novel gene delivery composite system based on biodegradable folate-poly (ester amine) polymer and thermosensitive hydrogel for sustained gene release

Local anti-oncogene delivery providing high local concentration of gene, increasing antitumor effect and decreasing systemic side effects is currently attracting interest in cancer therapy. In this paper, a novel local sustained anti-oncogene delivery system, PECE thermoresponsive hydrogel containin...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Zhao, Hang, Jia, YanPeng, Guo, QingFa, Qu, Ying, Su, Jing, Lu, XiaoLing, Zhao, YongXiang, Qian, ZhiYong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756671/
https://www.ncbi.nlm.nih.gov/pubmed/26883682
http://dx.doi.org/10.1038/srep21402