Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development

SUMO-specific protease 2 (SENP2) activities to remove SUMO from its substrates is essential for development of trophoblast stem cells, niches and lineages. Global deletion of SENP2 leads to midgestation lethality, and causes severe defects in the placenta which is accompanied by embryonic brain and...

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Detalles Bibliográficos
Autores principales: Maruyama, Eri O., Lin, Heng, Chiu, Shang-Yi, Yu, H.-M. Ivy, Porter, George A., Hsu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756675/
https://www.ncbi.nlm.nih.gov/pubmed/26883797
http://dx.doi.org/10.1038/srep20999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756675/
https://www.ncbi.nlm.nih.gov/pubmed/26883797
http://dx.doi.org/10.1038/srep20999

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