Dose- and time-dependent effects of actomyosin inhibition on live mouse outflow resistance and aqueous drainage tissues

Actomyosin contractility modulates outflow resistance of the aqueous drainage tissues and intraocular pressure, a key pathogenic factor of glaucoma. We established methodology to reliably analyze the effect of latrunculin-B (Lat-B)-induced actin depolymerization on outflow physiology in live mice. A...

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Detalles Bibliográficos
Autores principales: Ko, MinHee K., Kim, Eun Kyoung, Gonzalez, Jose M., Tan, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756686/
https://www.ncbi.nlm.nih.gov/pubmed/26884319
http://dx.doi.org/10.1038/srep21492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756686/
https://www.ncbi.nlm.nih.gov/pubmed/26884319
http://dx.doi.org/10.1038/srep21492

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