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Dose- and time-dependent effects of actomyosin inhibition on live mouse outflow resistance and aqueous drainage tissues
Actomyosin contractility modulates outflow resistance of the aqueous drainage tissues and intraocular pressure, a key pathogenic factor of glaucoma. We established methodology to reliably analyze the effect of latrunculin-B (Lat-B)-induced actin depolymerization on outflow physiology in live mice. A...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756686/ https://www.ncbi.nlm.nih.gov/pubmed/26884319 http://dx.doi.org/10.1038/srep21492 |