Cargando…

Oxidative stress contributes to the tamoxifen-induced killing of breast cancer cells: implications for tamoxifen therapy and resistance

Tamoxifen is the accepted therapy for patients with estrogen receptor-α (ERα)-positive breast cancer. However, clinical resistance to tamoxifen, as demonstrated by recurrence or progression on therapy, is frequent and precedes death from metastases. To improve breast cancer treatment it is vital to...

Descripción completa

Detalles Bibliográficos
Autores principales: Bekele, Raie T., Venkatraman, Ganesh, Liu, Rong-Zong, Tang, Xiaoyun, Mi, Si, Benesch, Matthew G. K., Mackey, John R., Godbout, Roseline, Curtis, Jonathan M., McMullen, Todd P. W., Brindley, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756695/
https://www.ncbi.nlm.nih.gov/pubmed/26883574
http://dx.doi.org/10.1038/srep21164