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Three-dimensional spherical spatial boundary conditions differentially regulate osteogenic differentiation of mesenchymal stromal cells

The spatial boundary condition (SBC) arising from the surrounding microenvironment imposes specific geometry and spatial constraints that affect organogenesis and tissue homeostasis. Mesenchymal stromal cells (MSCs) sensitively respond to alterations of mechanical cues generated from the SBC. Howeve...

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Detalles Bibliográficos
Autores principales: Lo, Yin-Ping, Liu, Yi-Shiuan, Rimando, Marilyn G., Ho, Jennifer Hui-Chun, Lin, Keng-hui, Lee, Oscar K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756701/
https://www.ncbi.nlm.nih.gov/pubmed/26884253
http://dx.doi.org/10.1038/srep21253