Deletion of GIRK2 Subunit of GIRK Channels Alters the 5-HT(1A) Receptor-Mediated Signaling and Results in a Depression-Resistant Behavior

BACKGROUND: Targeting dorsal raphe 5-HT(1A) receptors, which are coupled to G-protein inwardly rectifying potassium (GIRK) channels, has revealed their contribution not only to behavioral and functional aspects of depression but also to the clinical response to its treatment. Although GIRK channels...

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Detalles Bibliográficos
Autores principales: Llamosas, Nerea, Bruzos-Cidón, Cristina, Rodríguez, José Julio, Ugedo, Luisa, Torrecilla, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756724/
https://www.ncbi.nlm.nih.gov/pubmed/25956878
http://dx.doi.org/10.1093/ijnp/pyv051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756724/
https://www.ncbi.nlm.nih.gov/pubmed/25956878
http://dx.doi.org/10.1093/ijnp/pyv051

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