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On the impact of masking and blocking hypotheses for measuring the efficacy of new tuberculosis vaccines

Over the past 60 years, the Mycobacterium bovis bacille Calmette–Guérin (BCG) has been used worldwide to prevent tuberculosis (TB). However, BCG has shown a very variable efficacy in different trials, offering a wide range of protection in adults against pulmonary TB. One of the most accepted hypoth...

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Detalles Bibliográficos
Autores principales: Arregui, Sergio, Sanz, Joaquín, Marinova, Dessislava, Martín, Carlos, Moreno, Yamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756732/
https://www.ncbi.nlm.nih.gov/pubmed/26893956
http://dx.doi.org/10.7717/peerj.1513