Genome-wide CpG island methylation and intergenic demethylation propensities vary among different tumor sites

The epigenetic landscape of cancer includes both focal hypermethylation and broader hypomethylation in a genome-wide manner. By means of a comprehensive genomic analysis on 6637 tissues of 21 tumor types, we here show that the degrees of overall methylation in CpG island (CGI) and demethylation in i...

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Detalles Bibliográficos
Autores principales: Lee, Seung-Tae, Wiemels, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756811/
https://www.ncbi.nlm.nih.gov/pubmed/26464434
http://dx.doi.org/10.1093/nar/gkv1038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756811/
https://www.ncbi.nlm.nih.gov/pubmed/26464434
http://dx.doi.org/10.1093/nar/gkv1038

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