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Genome-wide CpG island methylation and intergenic demethylation propensities vary among different tumor sites
The epigenetic landscape of cancer includes both focal hypermethylation and broader hypomethylation in a genome-wide manner. By means of a comprehensive genomic analysis on 6637 tissues of 21 tumor types, we here show that the degrees of overall methylation in CpG island (CGI) and demethylation in i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756811/ https://www.ncbi.nlm.nih.gov/pubmed/26464434 http://dx.doi.org/10.1093/nar/gkv1038 |