HMGB1 interacts with XPA to facilitate the processing of DNA interstrand crosslinks in human cells

Many effective agents used in cancer chemotherapy cause DNA interstrand crosslinks (ICLs), which covalently link both strands of the double helix together resulting in cytotoxicity. ICLs are thought to be processed by proteins from a variety of DNA repair pathways; however, a clear understanding of...

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Detalles Bibliográficos
Autores principales: Mukherjee, Anirban, Vasquez, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756816/
https://www.ncbi.nlm.nih.gov/pubmed/26578599
http://dx.doi.org/10.1093/nar/gkv1183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756816/
https://www.ncbi.nlm.nih.gov/pubmed/26578599
http://dx.doi.org/10.1093/nar/gkv1183

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