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Targeted cross-linking-mass spectrometry determines vicinal interactomes within heterogeneous RNP complexes

Proteomic and RNomic approaches have identified many components of different ribonucleoprotein particles (RNPs), yet still little is known about the organization and protein proximities within these heterogeneous and highly dynamic complexes. Here we describe a targeted cross-linking approach, which...

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Detalles Bibliográficos
Autores principales: Trahan, Christian, Oeffinger, Marlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756821/
https://www.ncbi.nlm.nih.gov/pubmed/26657640
http://dx.doi.org/10.1093/nar/gkv1366