Structural requirements for protein-catalyzed annealing of U4 and U6 RNAs during di-snRNP assembly

Base-pairing of U4 and U6 snRNAs during di-snRNP assembly requires large-scale remodeling of RNA structure that is chaperoned by the U6 snRNP protein Prp24. We investigated the mechanism of U4/U6 annealing in vitro using an assay that enables visualization of ribonucleoprotein complexes and faithful...

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Detalles Bibliográficos
Autores principales: Didychuk, Allison L., Montemayor, Eric J., Brow, David A., Butcher, Samuel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756825/
https://www.ncbi.nlm.nih.gov/pubmed/26673715
http://dx.doi.org/10.1093/nar/gkv1374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756825/
https://www.ncbi.nlm.nih.gov/pubmed/26673715
http://dx.doi.org/10.1093/nar/gkv1374

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