An integrated systems biology approach identifies positive cofactor 4 as a factor that increases reprogramming efficiency

Spermatogonial stem cells (SSCs) can spontaneously dedifferentiate into embryonic stem cell (ESC)-like cells, which are designated as multipotent SSCs (mSSCs), without ectopic expression of reprogramming factors. Interestingly, SSCs express key pluripotency genes such as Oct4, Sox2, Klf4 and Myc. Th...

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Detalles Bibliográficos
Autores principales: Jo, Junghyun, Hwang, Sohyun, Kim, Hyung Joon, Hong, Soomin, Lee, Jeoung Eun, Lee, Sung-Geum, Baek, Ahmi, Han, Heonjong, Lee, Jin Il, Lee, Insuk, Lee, Dong Ryul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756831/
https://www.ncbi.nlm.nih.gov/pubmed/26740582
http://dx.doi.org/10.1093/nar/gkv1468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756831/
https://www.ncbi.nlm.nih.gov/pubmed/26740582
http://dx.doi.org/10.1093/nar/gkv1468

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