The use of modified and non-natural nucleotides provide unique insights into pro-mutagenic replication catalyzed by polymerase eta

This report evaluates the pro-mutagenic behavior of 8-oxo-guanine (8-oxo-G) by quantifying the ability of high-fidelity and specialized DNA polymerases to incorporate natural and modified nucleotides opposite this lesion. Although high-fidelity DNA polymerases such as pol δ and the bacteriophage T4...

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Detalles Bibliográficos
Autores principales: Choi, Jung-Suk, Dasari, Anvesh, Hu, Peter, Benkovic, Stephen J., Berdis, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756837/
https://www.ncbi.nlm.nih.gov/pubmed/26717984
http://dx.doi.org/10.1093/nar/gkv1509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756837/
https://www.ncbi.nlm.nih.gov/pubmed/26717984
http://dx.doi.org/10.1093/nar/gkv1509

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