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The DNA polymerase III holoenzyme contains γ and is not a trimeric polymerase

There is widespread agreement that the clamp loader of the Escherichia coli replicase has the composition DnaX(3)δδ’χψ. Two DnaX proteins exist in E. coli, full length τ and a truncated γ that is created by ribosomal frameshifting. τ binds DNA polymerase III tightly; γ does not. There is a controver...

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Detalles Bibliográficos
Autores principales: Dohrmann, Paul R., Correa, Raul, Frisch, Ryan L., Rosenberg, Susan M., McHenry, Charles S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756838/
https://www.ncbi.nlm.nih.gov/pubmed/26786318
http://dx.doi.org/10.1093/nar/gkv1510