Dynamics and recognition within a protein–DNA complex: a molecular dynamics study of the SKN-1/DNA interaction

Molecular dynamics simulations of the Caenorhabditis elegans transcription factor SKN-1 bound to its cognate DNA site show that the protein–DNA interface undergoes significant dynamics on the microsecond timescale. A detailed analysis of the simulation shows that movements of two key arginine side c...

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Detalles Bibliográficos
Autores principales: Etheve, Loïc, Martin, Juliette, Lavery, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756839/
https://www.ncbi.nlm.nih.gov/pubmed/26721385
http://dx.doi.org/10.1093/nar/gkv1511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756839/
https://www.ncbi.nlm.nih.gov/pubmed/26721385
http://dx.doi.org/10.1093/nar/gkv1511

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