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Dynamics and recognition within a protein–DNA complex: a molecular dynamics study of the SKN-1/DNA interaction
Molecular dynamics simulations of the Caenorhabditis elegans transcription factor SKN-1 bound to its cognate DNA site show that the protein–DNA interface undergoes significant dynamics on the microsecond timescale. A detailed analysis of the simulation shows that movements of two key arginine side c...
Autores principales: | Etheve, Loïc, Martin, Juliette, Lavery, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756839/ https://www.ncbi.nlm.nih.gov/pubmed/26721385 http://dx.doi.org/10.1093/nar/gkv1511 |
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