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Lineage-specific variations in the trigger loop modulate RNA proofreading by bacterial RNA polymerases
RNA cleavage by bacterial RNA polymerase (RNAP) has been implicated in transcriptional proofreading and reactivation of arrested transcription elongation complexes but its molecular mechanism is less understood than the mechanism of nucleotide addition, despite both reactions taking place in the sam...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756841/ https://www.ncbi.nlm.nih.gov/pubmed/26733581 http://dx.doi.org/10.1093/nar/gkv1521 |