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Lineage-specific variations in the trigger loop modulate RNA proofreading by bacterial RNA polymerases

RNA cleavage by bacterial RNA polymerase (RNAP) has been implicated in transcriptional proofreading and reactivation of arrested transcription elongation complexes but its molecular mechanism is less understood than the mechanism of nucleotide addition, despite both reactions taking place in the sam...

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Detalles Bibliográficos
Autores principales:	Esyunina, Daria, Turtola, Matti, Pupov, Danil, Bass, Irina, Klimašauskas, Saulius, Belogurov, Georgiy, Kulbachinskiy, Andrey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756841/ https://www.ncbi.nlm.nih.gov/pubmed/26733581 http://dx.doi.org/10.1093/nar/gkv1521

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