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Locked and proteolysis-based transcription activator-like effector (TALE) regulation

Development of orthogonal, designable and adjustable transcriptional regulators is an important goal of synthetic biology. Their activity has been typically modulated through stimulus-induced oligomerization or interaction between the DNA-binding and activation/repression domain. We exploited a feat...

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Detalles Bibliográficos
Autores principales: Lonzarić, Jan, Lebar, Tina, Majerle, Andreja, Manček-Keber, Mateja, Jerala, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756844/
https://www.ncbi.nlm.nih.gov/pubmed/26748097
http://dx.doi.org/10.1093/nar/gkv1541