Targeted single molecule mutation detection with massively parallel sequencing

Next-generation sequencing (NGS) technologies have transformed genomic research and have the potential to revolutionize clinical medicine. However, the background error rates of sequencing instruments and limitations in targeted read coverage have precluded the detection of rare DNA sequence variant...

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Detalles Bibliográficos
Autores principales: Gregory, Mark T., Bertout, Jessica A., Ericson, Nolan G., Taylor, Sean D., Mukherjee, Rithun, Robins, Harlan S., Drescher, Charles W., Bielas, Jason H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756847/
https://www.ncbi.nlm.nih.gov/pubmed/26384417
http://dx.doi.org/10.1093/nar/gkv915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756847/
https://www.ncbi.nlm.nih.gov/pubmed/26384417
http://dx.doi.org/10.1093/nar/gkv915

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