A novel high-throughput activity assay for the Trypanosoma brucei editosome enzyme REL1 and other RNA ligases

The protist parasite Trypanosoma brucei causes Human African trypanosomiasis (HAT), which threatens millions of people in sub-Saharan Africa. Without treatment the infection is almost always lethal. Current drugs for HAT are difficult to administer and have severe side effects. Together with increas...

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Detalles Bibliográficos
Autores principales: Zimmermann, Stephan, Hall, Laurence, Riley, Sean, Sørensen, Jesper, Amaro, Rommie E., Schnaufer, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756849/
https://www.ncbi.nlm.nih.gov/pubmed/26400159
http://dx.doi.org/10.1093/nar/gkv938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756849/
https://www.ncbi.nlm.nih.gov/pubmed/26400159
http://dx.doi.org/10.1093/nar/gkv938

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