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A novel high-throughput activity assay for the Trypanosoma brucei editosome enzyme REL1 and other RNA ligases
The protist parasite Trypanosoma brucei causes Human African trypanosomiasis (HAT), which threatens millions of people in sub-Saharan Africa. Without treatment the infection is almost always lethal. Current drugs for HAT are difficult to administer and have severe side effects. Together with increas...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756849/ https://www.ncbi.nlm.nih.gov/pubmed/26400159 http://dx.doi.org/10.1093/nar/gkv938 |