Ultra-fast local-haplotype variant calling using paired-end DNA-sequencing data reveals somatic mosaicism in tumor and normal blood samples

Somatic mosaicism refers to the existence of somatic mutations in a fraction of somatic cells in a single biological sample. Its importance has mainly been discussed in theory although experimental work has started to emerge linking somatic mosaicism to disease diagnosis. Through novel statistical m...

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Detalles Bibliográficos
Autores principales: Sengupta, Subhajit, Gulukota, Kamalakar, Zhu, Yitan, Ober, Carole, Naughton, Katherine, Wentworth-Sheilds, William, Ji, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756850/
https://www.ncbi.nlm.nih.gov/pubmed/26420835
http://dx.doi.org/10.1093/nar/gkv953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756850/
https://www.ncbi.nlm.nih.gov/pubmed/26420835
http://dx.doi.org/10.1093/nar/gkv953

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