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Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites

Laser microirradiation is a powerful tool for real-time single-cell analysis of the DNA damage response (DDR). It is often found, however, that factor recruitment or modification profiles vary depending on the laser system employed. This is likely due to an incomplete understanding of how laser cond...

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Detalles Bibliográficos
Autores principales: Saquilabon Cruz, Gladys Mae, Kong, Xiangduo, Silva, Bárbara Alcaraz, Khatibzadeh, Nima, Thai, Ryan, Berns, Michael W., Yokomori, Kyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756852/
https://www.ncbi.nlm.nih.gov/pubmed/26424850
http://dx.doi.org/10.1093/nar/gkv976