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Tissue Specific Expression of Cre in Rat Tyrosine Hydroxylase and Dopamine Active Transporter-Positive Neurons

The rat is a preferred model system over the mouse for neurological studies, and cell type-specific Cre expression in the rat enables precise ablation of gene function in neurons of interest, which is especially valuable for neurodegenerative disease modeling and optogenetics. Yet, few such Cre rats...

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Detalles Bibliográficos
Autores principales: Liu, Zhenyi, Brown, Andrew, Fisher, Dan, Wu, Yumei, Warren, Joe, Cui, Xiaoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757100/
https://www.ncbi.nlm.nih.gov/pubmed/26886559
http://dx.doi.org/10.1371/journal.pone.0149379