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Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence

Although sphingosine 1-phosphate (S1P) has been reported to play an important role in cancer pathophysiology, little is known about S1P and hepatocellular carcinoma (HCC). To clarify the relationship between S1P and HCC, 77 patients with HCC who underwent surgical treatment were consecutively enroll...

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Detalles Bibliográficos
Autores principales: Uranbileg, Baasanjav, Ikeda, Hitoshi, Kurano, Makoto, Enooku, Kenichiro, Sato, Masaya, Saigusa, Daisuke, Aoki, Junken, Ishizawa, Takeaki, Hasegawa, Kiyoshi, Kokudo, Norihiro, Yatomi, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757388/
https://www.ncbi.nlm.nih.gov/pubmed/26886371
http://dx.doi.org/10.1371/journal.pone.0149462