Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling

Melanoma is the most lethal form of skin cancer and successful treatment of metastatic melanoma remains challenging. BRAF/MEK inhibitors only show a temporary benefit due to rapid occurrence of resistance, whereas immunotherapy is mainly effective in selected subsets of patients. Thus, there is a ne...

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Detalles Bibliográficos
Autores principales: Kruiswijk, F, Hasenfuss, S C, Sivapatham, R, Baar, M P, Putavet, D, Naipal, K A T, van den Broek, N J F, Kruit, W, van der Spek, P J, van Gent, D C, Brenkman, A B, Campisi, J, Burgering, B M T, Hoeijmakers, J H J, de Keizer, P L J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757516/
https://www.ncbi.nlm.nih.gov/pubmed/26279295
http://dx.doi.org/10.1038/onc.2015.282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757516/
https://www.ncbi.nlm.nih.gov/pubmed/26279295
http://dx.doi.org/10.1038/onc.2015.282

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